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What Is Susten 200 Tablet? Its Uses and Role in Pregnancy
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MBBS, MS (OBS & Gynae) · 4 years experience
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- Susten 200 tablet contains progesterone, a natural hormone that thickens the uterine lining, supports implantation, and helps maintain a healthy pregnancy by preventing uterine contractions.
- Doctors prescribe Susten 200 in pregnancy to reduce miscarriage risk, support an incompetent cervix, and prevent premature delivery in women with low progesterone levels.
- Susten 200 is usually prescribed during the first trimester up to the 12th or 20th week, with possible side effects like nausea, breast tenderness, and headache.
- What else can support a healthy pregnancy journey? Explore our Baby Wellness Kit | Skincare Gift Set for Newborns.
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4.5If your doctor has prescribed Susten 200 during pregnancy, you may be wondering what it does and why you need it. Susten 200 is a common progesterone supplement used to support early pregnancy, especially when there is a risk of miscarriage or a history of pregnancy loss. This article explains what Susten 200 is, why it is prescribed, how it helps, how to take it safely, and what the current medical evidence actually shows.
At a glance Susten 200 contains 200 mg of natural micronised progesterone, a hormone that helps prepare and maintain the uterine lining for a growing pregnancy. Doctors prescribe it mainly to support pregnancies at higher risk of miscarriage or preterm birth. It works best for specific groups, such as women with early bleeding and previous miscarriages, and should always be taken exactly as prescribed. |
What Is Susten 200?
Susten 200 is a brand of micronised progesterone, with each capsule containing 200 mg of the hormone progesterone. Progesterone is a natural hormone your body produces after ovulation and throughout pregnancy. It thickens the endometrium (the lining of the uterus), helps a fertilised egg implant, and keeps the uterus stable so a pregnancy can continue. When your body's natural progesterone is low, or when extra support is needed after fertility treatment or in a pregnancy considered at risk, doctors may prescribe Susten 200 to top up these levels. It is available as a capsule that can be taken by mouth or placed in the vagina, depending on your doctor's advice.
Why Is Susten 200 Prescribed During Pregnancy?
Progesterone is essential for a healthy pregnancy: it maintains the uterine lining, supports the growth of the placenta, and helps keep the uterus relaxed so it does not contract too early. In some pregnancies, because of low progesterone, previous pregnancy loss, fertility treatment, or a short or weak cervix, this natural support may not be enough. Susten 200 is prescribed to supplement progesterone in these situations, giving the pregnancy extra hormonal support during its most vulnerable early stages.
How Does Susten 200 Help, and What Does the Research Show?
Susten 200 works by raising progesterone levels so the uterus can better support a developing pregnancy. Depending on your situation, it may be prescribed for:
Why it's prescribed | How Susten 200 helps |
Threatened miscarriage | For women with early-pregnancy bleeding and a previous miscarriage, vaginal progesterone can improve the chance of a live birth (PRISM trial, 2019). |
Recurrent loss & IVF | Provides luteal-phase (post-ovulation) support after fertility treatment and in some cases of recurrent pregnancy loss. |
Short cervix / preterm risk | In women with a short cervix, daily vaginal progesterone lowers the risk of premature delivery. |
Cervical insufficiency | May be used alongside other measures to support a weak (incompetent) cervix. |
The evidence is strongest for women who have both early bleeding and a history of miscarriage. The large UK PRISM trial found no overall benefit for every woman with early bleeding, but women with three or more previous losses had markedly more live births with progesterone (72% versus 57%). This is why current UK guidance recommends micronised vaginal progesterone specifically for women with early-pregnancy bleeding and a previous miscarriage.
How Do You Take Susten 200, and for How Long?
Susten 200 can be taken by mouth or inserted into the vagina, based on your doctor's instructions; the vaginal route delivers progesterone directly to the uterus and often causes fewer whole-body side effects. The dose and duration depend on why it has been prescribed. For early bleeding with a previous miscarriage, guidelines suggest continuing until about 16 weeks once a heartbeat is confirmed, while other prescriptions may run through the first trimester (around 12 weeks) or up to 20 weeks. Take it at the same time each day, do not change the dose on your own, and never stop suddenly without medical advice. If you miss a dose, take it as soon as you remember, unless it is nearly time for the next one.
Evidence-based note Progesterone is not a one-size-fits-all treatment. The strongest evidence supports its use in women who have early-pregnancy bleeding together with a history of miscarriage, not in every pregnancy. This is why your doctor weighs your personal and pregnancy history before prescribing Susten 200, and why you should never start or stop it on your own. |
Frequently Asked Questions About Susten 200
Can Susten 200 cause birth defects?
Current evidence does not show that micronised progesterone causes birth defects. It is the same hormone your body makes naturally, and large trials such as PRISM found no significant increase in congenital abnormalities. Always use it only as prescribed.
Can Susten 200 cause a false positive pregnancy test?
No. Home pregnancy tests detect the hormone hCG, not progesterone. Because Susten 200 contains only progesterone, it does not affect urine pregnancy test results or cause a false positive. If in doubt, confirm with your doctor.
Is Susten 200 safe during breastfeeding?
Susten 200 is mainly used during pregnancy rather than while breastfeeding. Only small amounts of progesterone pass into breast milk and it is generally considered low-risk, but you should always follow your doctor's advice before using it while nursing.
What are the common side effects of Susten 200?
Most side effects are mild and may include breast tenderness, nausea, dizziness, drowsiness, headache, bloating, or mild vaginal irritation with the vaginal form. Tell your doctor if any symptom is severe or does not go away.
The Bottom Line
Susten 200 is a progesterone supplement that helps maintain the uterine lining and support pregnancy, particularly in women at higher risk of miscarriage or preterm birth. It works best for specific groups rather than everyone, so it should only be taken as prescribed. If you have any concerns about your dose, side effects, or when to stop, speak with your doctor before making changes.
Sources and Related Reading
Authoritative sources
● Coomarasamy A, et al. A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy (PRISM). New England Journal of Medicine, 2019.
● NICE / Scottish Government guidance on the use of progesterone in the management of threatened and recurrent miscarriage, 2021.
● Romero R, et al. Vaginal progesterone for preventing preterm birth in singleton gestations with a short cervix: an individual patient data meta-analysis. American Journal of Obstetrics & Gynecology, 2018.
● Wahabi HA, et al. Progestogen for treating threatened miscarriage. Cochrane Database of Systematic Reviews, 2018.
Related reading on Mylo
● When to Stop Susten 200 During Pregnancy
● Hydroxyprogesterone Injection During Pregnancy: What You Need to Know
● Miscarriage During Early Pregnancy: Causes, Symptoms & How to Avoid
● Incompetent Cervix: Causes, Symptoms & Treatment
● Preterm Labour: Meaning, Symptoms & Causes
Disclaimer: This article is for general information only and is not a substitute for professional medical advice. Always consult your doctor before starting, changing, or stopping any medication during pregnancy.
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Medical Disclaimer
This content is for informational purposes only and should not replace professional medical advice. Consult with a physician or other health care professional if you have any concerns or questions about your health. If you rely on the information provided here, you do so solely at your own risk.
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